2C-G-5 Fumarate

Product Content – 2C-G-5 Fumarate

• IUPAC Name: 2-(2,5-dimethoxy-3,4-dimethylphenyl)-N-ethylethanamine fumarate
• Molecular Formula: C₁₄H₂₁NO₂ · C₄H₄O₄
• CAS Registry Number: 207740-20-3
• Salt Form: Fumarate (1:1) – improves crystallinity, shelf-life and water solubility compared with the free-base.

• Appearance: Off-white to pale-pink crystalline powder ≥ 97 % (HPLC)
• Melting Point: 158 – 162 °C (dec.)
• Solubility: ~ 12 mg mL⁻¹ in pH 4-5 buffer; sparingly soluble in water; freely soluble in DMSO & 10 % β-cyclodextrin.
• Storage: Keep tightly sealed, −20 °C, desiccated and protected from light; stable ≥ 24 months under these conditions.
• Shipping: Ambient; no special dangerous-goods classification (research chemical, not scheduled in most jurisdictions; user must verify local law).

• Class: 2C-series phenethylamine, 2,5-dimethoxy-3,4-dimethyl substitution pattern.
• Relevant Potency: Active at 10–16 mg (free-base equivalent) in anecdotal literature; duration 32–48 h.
• Primary Mode: 5-HT₂A/₂C agonism with additional trace amine-associated receptor (TAAR) activity; minimal dopaminergic or adrenergic affinity (Ki > 10 µM).
• Reported Effects (PiHKAL): Mild 2C-B-like euphoria, gradual onset, prolonged residual stimulation; visual component weaker than 2C-B; occasional irritability during offset phase.
• Metabolism: Hepatic O-demethylation followed by sulphate/glucuronide conjugation; CYP2D6 minor contribution.

• Status: Research chemical – NOT for human or veterinary use.
• PPE: Handle with gloves, goggles, FFP-2 respirator when weighing dry powder; work inside a ventilated enclosure.
• Exclusions: Do not supply to minors. Customer must possess appropriate DEA/ACMD or equivalent research licence where applicable.
• Documentation: Batch-specific ¹H-NMR, ¹³C-NMR, HPLC purity, fumarate content (≤ 0.2 % excess fumaric acid), residual solvent (ICH Q3C) and heavy-metal report provided via QR-coded COA.